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NEET UG Molecular Basis of Inheritance — practice questions

Explore 29 free Molecular Basis of Inheritance questions in NEET UG Biology. Open each question or exercise to read its content, reference answers and available explanation.

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Molecular Basis of Inheritance questions and exercises with answers

Showing questions 1–29 of 29.

DNA was first identified as an acidic substance in the nucleus by:Read the answer and worked solution →In the Watson-Crick double helix, adenine pairs with thymine via how many hydrogen bonds?Read the answer and worked solution →In a DNA molecule with 20% cytosine, what is the percentage of adenine?Read the answer and worked solution →What is the haploid DNA content of a human cell, in base pairs?Read the answer and worked solution →Which bond links a nitrogenous base to the pentose sugar in a nucleoside?Read the answer and worked solution →Why is the distance between the two strands of DNA nearly uniform?Read the answer and worked solution →A mammalian cell has 6.6 x 10^9 bp at 0.34 nm per bp. Its DNA length is aboutRead the answer and worked solution →E. coli DNA is 1.36 mm long. At 0.34 nm per base pair, how many bp does it hold?Read the answer and worked solution →In E. coli, DNA held by positively charged proteins lies in a region called theRead the answer and worked solution →About how many base pairs of DNA helix does a typical nucleosome contain?Read the answer and worked solution →Which chromatin is loosely packed, stains light and is transcriptionally active?Read the answer and worked solution →In Griffith's experiment, which injection made the mice die?Read the answer and worked solution →Before Avery, MacLeod and McCarty, the genetic material was thought to beRead the answer and worked solution →Which of these uses RNA rather than DNA as its genetic material?Read the answer and worked solution →Why do viruses with RNA genomes evolve faster than others?Read the answer and worked solution →Which feature gives DNA extra stability compared with RNA?Read the answer and worked solution →E. coli divides every 20 min. After 80 min in 14N, the light to hybrid DNA ratio isRead the answer and worked solution →Meselson and Stahl separated 15N DNA from 14N DNA usingRead the answer and worked solution →Taylor and colleagues showed semiconservative replication in chromosomes ofRead the answer and worked solution →Besides acting as substrates in replication, deoxynucleoside triphosphatesRead the answer and worked solution →Replication is discontinuous on the template strand with which polarity?Read the answer and worked solution →Structural genes coding several polypeptides in one unit, as in bacteria, areRead the answer and worked solution →Which physicist argued that the genetic code must use three nucleotides?Read the answer and worked solution →Har Gobind Khorana helped crack the genetic code mainly byRead the answer and worked solution →Exceptions to the universal genetic code are seen inRead the answer and worked solution →Inserting exactly three bases into a structural gene usuallyRead the answer and worked solution →Before its adapter role was known, tRNA was calledRead the answer and worked solution →In its actual three-dimensional form, a tRNA molecule looks likeRead the answer and worked solution →Linking an ATP-activated amino acid to its cognate tRNA is calledRead the answer and worked solution →

Worked practice questions

DNA was first identified as an acidic substance in the nucleus by:

  1. Watson and Crick (1953)
  2. Erwin Chargaff
  3. Hershey and Chase (1952)
  4. Friedrich Meischer (1869) — named it 'Nuclein'
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Correct answer: D. Friedrich Meischer (1869) — named it 'Nuclein'

**Friedrich Meischer** isolated DNA from pus cells in 1869 and named the acidic substance **'Nuclein'**. The structure took another 80+ years to elucidate (Watson-Crick, 1953).

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In the Watson-Crick double helix, adenine pairs with thymine via how many hydrogen bonds?

  1. 3
  2. 1
  3. 2
  4. 4
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Correct answer: C. 2

**A=T → 2 H-bonds**. **G≡C → 3 H-bonds**. GC-rich DNA is more thermostable than AT-rich because of the stronger G-C pairing.

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In a DNA molecule with 20% cytosine, what is the percentage of adenine?

  1. 30%
  2. 60%
  3. 20%
  4. 50%
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Correct answer: A. 30%

**Chargaff:** C = G = 20%, so C + G = 40%. Hence A + T = 60%. Since A = T, **A = 30%**.

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