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Which enzyme joins the discontinuously synthesised Okazaki fragments on the lagging strand?
A{'text': 'DNA ligase', 'label': 'A'}
B{'text': 'DNA helicase', 'label': 'B'}
C{'text': 'DNA primase', 'label': 'C'}
D{'text': 'DNA polymerase III', 'label': 'D'}
Answer & Solution
Correct answer: A. {'text': 'DNA ligase', 'label': 'A'}
Because DNA polymerase only adds nucleotides 5' to 3', the lagging strand is built as Okazaki fragments which are then sealed by DNA ligase. Helicase unwinds, primase lays RNA primers, and pol III extends them.
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