Which enzyme joins the discontinuously synthesised Okazaki fragments on the lagging strand?
ADNA ligase
BDNA helicase
CDNA primase
DDNA polymerase III
Answer & Solution
Correct answer: A. DNA ligase
Because DNA polymerase only adds nucleotides 5' to 3', the lagging strand is built as Okazaki fragments which are then sealed by DNA ligase.
Helicase unwinds, primase lays RNA primers, and pol III extends them.
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