allerySickle-cell anemia is caused by a point mutation in the beta-globin gene that substitutes:
AGlutamate for valine
BLysine for arginine
CMethionine for valine
DValine for glutamate
Answer & Solution
Correct answer: D. Valine for glutamate
A single base change in the beta-globin gene replaces glutamate (Glu) with valine (Val) at position 6, producing HbS.
This is the classic missense point mutation in your syllabus.
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