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DNA was first identified as an acidic substance in the nucleus by:

AWatson and Crick (1953)
BErwin Chargaff
CHershey and Chase (1952)
DFriedrich Meischer (1869) — named it 'Nuclein'
Answer & Solution
Correct answer: D. Friedrich Meischer (1869) — named it 'Nuclein'
**Friedrich Meischer** isolated DNA from pus cells in 1869 and named the acidic substance **'Nuclein'**. The structure took another 80+ years to elucidate (Watson-Crick, 1953).
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