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Which of the following best supports the 'RNA world' hypothesis?
ARNA is more stable than DNA
BDNA cannot replicate without RNA
CRNA is found only in viruses
DRNA can act as both genetic material AND as a catalyst (ribozyme — e.g., 23S rRNA in peptide bond formation); essential life processes evolved around RNA
Answer & Solution
Correct answer: D. RNA can act as both genetic material AND as a catalyst (ribozyme — e.g., 23S rRNA in peptide bond formation); essential life processes evolved around RNA
**RNA world hypothesis**: RNA was the first genetic material. Evidence: (i) RNA can catalyse reactions (ribozymes — e.g., 23S rRNA peptidyl transferase, self-splicing introns); (ii) essential life processes (translation, splicing) evolved around RNA; (iii) DNA evolved later as a more stable storage form.
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