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For a cell reaction reversed in direction, E° becomes:

ADoubled
BNegative (sign flip): E°(reverse) = -E°(forward)
CZero
DSame
Answer & Solution
Correct answer: B. Negative (sign flip): E°(reverse) = -E°(forward)
Reversing the cell reaction flips the role of anode/cathode, so E° flips sign. For example, Cu | Cu²⁺ || Zn²⁺ | Zn would have E° = -1.10 V (non-spontaneous; needs external energy to drive).
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