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Tetanus and diphtheria vaccines are made from bacterial toxins that have been inactivated. What are such vaccines called?
AToxoid vaccines
BSubunit vaccines
CConjugate vaccines
DRecombinant vaccines
Answer & Solution
Correct answer: A. Toxoid vaccines
1. Tetanus and diphtheria bacteria cause disease by producing toxins rather than by invading tissue widely.
2. Those protein toxins are inactivated using heat, chemicals or other methods.
3. A vaccine made from an inactivated toxin is a toxoid, and it teaches the immune system to recognise and eliminate the toxin.
4. Subunit vaccines contain a portion of the organism, and conjugate vaccines link a polysaccharide to a protein, so neither describes an inactivated toxin.
_Source: CDC Epidemiology and Prevention of Vaccine-Preventable Diseases (Pink Book), section Inactivated Vaccines_
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