What defines the primary structure of a protein?
AThe local folding of the chain into a helix or sheet
BThe unique sequence of amino acids in the chain
CThe way separate subunits associate with one another
DThe three dimensional shape the folded chain takes
Answer & Solution
Correct answer: B. The unique sequence of amino acids in the chain
1. There are four levels of protein structure: primary, secondary, tertiary and quaternary.
2. The primary structure is the unique sequence of amino acids in a polypeptide chain.
3. Local folding into an alpha helix or beta pleated sheet is the secondary structure.
4. The overall three dimensional shape is the tertiary structure, and the association of subunits is the quaternary structure.
_Source: OpenStax Biology (1st ed., CC BY 4.0), Ch 3 "Biological Macromolecules", section 3.4 Proteins_
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