Even though RNA is single stranded, what shape does most RNA still take?
AA shapeless chain with no folding of any kind
BA predictable three dimensional folded structure
CA double helix identical to that formed by DNA
DA flat ring closed by one phosphodiester linkage
Answer & Solution
Correct answer: B. A predictable three dimensional folded structure
1. RNA is usually single stranded, so it has no partner strand to pair with.
2. It can still pair with itself, because complementary sequences occur within the same molecule.
3. Most RNA types show extensive intramolecular base pairing of this kind.
4. That internal pairing creates a predictable three dimensional structure.
5. The structure is essential for the function of the molecule, so shape matters for RNA as it does for proteins.
6. A shapeless chain would contradict the observed pairing.
7. It is not a DNA style double helix, since the pairing is within one molecule rather than between two strands.
_Source: OpenStax Biology (1st ed., CC BY 4.0), Ch 3 "Biological Macromolecules", section 3.5 Nucleic Acids_
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