If one DNA strand reads AATTGGCC, what does its complementary strand read?
AAATTGGCC
BTTAACCGG
CGGCCAATT
DUUAACCGG
Answer & Solution
Correct answer: B. TTAACCGG
1. Only certain base pairings are allowed, so a given purine pairs with a given pyrimidine.
2. Adenine pairs with thymine and guanine pairs with cytosine, which is the base complementary rule.
3. Apply it position by position to AATTGGCC.
4. The two A bases give T, the two T bases give A, the two G bases give C and the two C bases give G.
5. The complementary strand therefore reads TTAACCGG.
6. The option with U belongs to RNA, since DNA carries thymine rather than uracil.
_Source: OpenStax Biology (1st ed., CC BY 4.0), Ch 3 "Biological Macromolecules", section 3.5 Nucleic Acids_
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