alleryStart learning →How many amino acids does human cytochrome c contain, and how many are conserved across species?
A147 in total, of which 37 hold the same position
B104 in total, of which 44 hold the same position
C104 in total, of which 37 hold the same position
D600 in total, of which 37 hold the same position
Answer & Solution
Correct answer: C. 104 in total, of which 37 hold the same position
1. Cytochrome c is part of the electron transport chain and is normally found in the mitochondrion.
2. Because its role in producing cellular energy is crucial, it has changed very little over millions of years.
3. Human cytochrome c contains 104 amino acids.
4. Across every cytochrome c sequenced so far, 37 of those amino acids appear in the same position.
5. That conservation points to a common ancestor.
6. The number 147 belongs to the beta chain of hemoglobin, and 600 is the approximate total for a whole hemoglobin molecule.
7. The number 44 is the position at which the human and yeast sequences differ, not a count of conserved residues.
_Source: OpenStax Biology (1st ed., CC BY 4.0), Ch 3 "Biological Macromolecules", section 3.4 Proteins_
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