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MP Board Class 12 (MPBSE) Molecular Basis of Inheritance — practice questions

Explore 25 free Molecular Basis of Inheritance questions in MP Board Class 12 (MPBSE) Biology. Open each question or exercise to read its content, reference answers and available explanation.

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Molecular Basis of Inheritance questions and exercises with answers

Showing questions 1–25 of 25.

In a DNA double helix, adenine pairs with thymine throughRead the answer and worked solution →The two strands of a DNA double helix areRead the answer and worked solution →A nucleosome consists ofRead the answer and worked solution →The Hershey-Chase experiment used radioactive isotopes to labelRead the answer and worked solution →The Meselson-Stahl experiment proved that DNA replication isRead the answer and worked solution →DNA polymerase synthesises a new DNA strand in which direction?Read the answer and worked solution →The central dogma of molecular biology states the flow of information asRead the answer and worked solution →During transcription, the strand of DNA actually read by RNA polymerase isRead the answer and worked solution →Introns are best described asRead the answer and worked solution →Which eukaryotic RNA polymerase synthesises the mRNA precursor (hnRNA)?Read the answer and worked solution →The total number of possible codons in the genetic code isRead the answer and worked solution →Which of the following is the universal start codon?Read the answer and worked solution →Approximately how much of the human genome codes for proteins?Read the answer and worked solution →In DNA, Adenine (A) pairs with Thymine (T) via:Read the answer and worked solution →The Hershey-Chase experiment (1952) proved that:Read the answer and worked solution →The Central Dogma of molecular biology states that genetic information flows:Read the answer and worked solution →Okazaki fragments are produced during DNA replication on which strand?Read the answer and worked solution →The START codon in eukaryotic mRNA translation is:Read the answer and worked solution →Translation of mRNA into protein occurs on which cellular structure?Read the answer and worked solution →The Lac Operon in E. coli is INDUCED (turned ON) by the presence of:Read the answer and worked solution →The Human Genome Project (HGP) ran from 1990 to:Read the answer and worked solution →During transcription, the enzyme that synthesises mRNA from DNA is:Read the answer and worked solution →DNA or RNA?Read the answer and worked solution →Order the flow of genetic informationRead the answer and worked solution →Naming the processesRead the answer and worked solution →

Worked practice questions

In a DNA double helix, adenine pairs with thymine through

  1. one hydrogen bond
  2. two hydrogen bonds
  3. three hydrogen bonds
  4. a covalent bond
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Correct answer: B. two hydrogen bonds

A and T form two hydrogen bonds; G and C form three. The unequal counts explain why G-C-rich regions are more thermally stable than A-T-rich regions.

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The two strands of a DNA double helix are

  1. parallel and right-handed
  2. parallel and left-handed
  3. anti-parallel and right-handed
  4. anti-parallel and left-handed
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Correct answer: C. anti-parallel and right-handed

Watson-Crick showed that the two strands run anti-parallel (one 5′→3′, the other 3′→5′) and coil in a right-handed spiral. Pitch ≈ 3.4 nm, ~10 bp per turn.

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A nucleosome consists of

  1. 200 bp of DNA wrapped around an octamer of histones
  2. 100 bp of DNA wrapped around a tetramer of histones
  3. 200 bp of RNA wrapped around four histones
  4. DNA without any protein
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Correct answer: A. 200 bp of DNA wrapped around an octamer of histones

**A nucleosome is the basic packing unit:** ~200 bp of DNA wound around a core of eight histone proteins (the histone octamer). Strings of nucleosomes form the chromatin fibre.

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