Which stomach hormone is produced mainly in the fundus and regulates food intake by stimulating hunger, with levels rising just before meals?

1. Several hormones secreted by the stomach act on targets beyond the stomach itself. 2. Ghrelin is produced by the stomach mucosa, mainly in the fundus. 3. Its production is stimulated by the fasting state, with levels increasing just prior to meals, and it acts on the hypothalamus to regulate food intake by stimulating hunger and satiety. 4. Gastrin mainly targets gastric glands and intestinal motility rather than regulating hunger from the hypothalamus. 5. Somatostatin instead restricts secretions and motility, the opposite kind of action from stimulating hunger. 6. Serotonin contracts stomach muscle, a local mechanical action rather than the hypothalamic hunger signal described here. _Source: OpenStax Anatomy and Physiology (CC BY 4.0), Ch 23 "The Digestive System", section 23.4, p. 1110_