Binding of tissue factor to a matrix factor produces which combination of effects?
APlatelets disperse and the vessel widens
BPlatelets adhere and the vessel widens
CPlatelets adhere and the vessel narrows
DPlatelets disperse and the vessel narrows
Answer & Solution
Correct answer: C. Platelets adhere and the vessel narrows
1. Tissue factor is displayed by the damaged cells lining the vessel.
2. It binds with another factor present in the extracellular matrix.
3. That binding causes platelets to adhere to the wall of the damaged vessel.
4. It also stimulates the adjacent smooth muscle cells to contract.
5. Contraction of those smooth muscle cells constricts the vessel, so the vessel narrows.
6. It further initiates steps that stimulate the platelets to produce clotting factors.
7. Adhering platelets plus a narrowing vessel is therefore the pairing, and any answer with dispersing platelets or a widening vessel reverses it.
_Source: OpenStax Biology (1st ed., CC BY 4.0), Ch 4 "Cell Structure", section 4.6 Connections between Cells and Cellular Activities_
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