Which two proteins predominantly hold a tight junction together?
ACadherins and connexins
BActins and myosins
CClaudins and occludins
DCollagens and keratins
Answer & Solution
Correct answer: C. Claudins and occludins
1. A tight junction is a watertight seal between two adjacent animal cells.
2. The cells are held tightly against each other by proteins.
3. The two named as predominant are claudins and occludins.
4. Cadherins build desmosomes and connexins build gap junctions, so that pair belongs to other junction types.
5. Tight junctions rest on claudins and occludins.
6. Actin and myosin are a motor pair working inside the cell, so they do not seal one cell against the next.
_Source: OpenStax Biology (1st ed., CC BY 4.0), Ch 4 "Cell Structure", section 4.6 Connections between Cells and Cellular Activities_
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