Lowe disease is caused by a mutation on which chromosome?

1. Lowe disease is a genetic disease caused by a mutation on the X chromosome. 2. Females possess two X chromosomes and males possess one X and one Y. 3. In females the genes on only one of the two X chromosomes are expressed, so a carrier has a 50 to 50 chance of having the disease. 4. Males have only one X chromosome and its genes are always expressed, so a male whose X carries the gene always has the disease. 5. The mutation lies on the X chromosome. _Source: OpenStax Biology (1st ed., CC BY 4.0), Ch 4 "Cell Structure", section 4.4 The Endomembrane System and Proteins_