In celiac disease, the immune response to gluten damages which structure?
AThe lysosomes of gut cells
BThe tight junctions of skin
CThe microvilli of gut cells
DThe peroxisomes of the liver
Answer & Solution
Correct answer: C. The microvilli of gut cells
1. Gluten is a protein found in wheat, barley and rye.
2. People with celiac disease mount an immune response against it.
3. That response damages the microvilli, the absorptive projections of the intestinal lining.
4. With the microvilli damaged the patient cannot absorb nutrients, which leads to malnutrition, cramping and diarrhea.
5. The damaged structures are the microvilli of the gut cells.
_Source: OpenStax Biology (1st ed., CC BY 4.0), Ch 4 "Cell Structure", section 4.3 Eukaryotic Cells_
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