alleryThe 'one gene - one polypeptide' concept was proposed by
ABeadle and Tatum
BWatson and Crick
CHershey and Chase
DKhorana
Answer & Solution
Correct answer: A. Beadle and Tatum
1. Beadle and Tatum's experiments on Neurospora mutants linked specific gene mutations to loss of specific enzymes.
2. They originally framed it as 'one gene - one enzyme'.
3. It was later refined to 'one gene - one polypeptide' to include subunits.
_Source: Maharashtra Balbharati Std XII Biology, Ch 4 "Molecular Basis of Inheritance" §4.7_
Keep practising Unit 6A: DNA and RNA Structure & Replication
Browse all Unit 6A: DNA and RNA Structure & Replication questions for AP Biology, or explore more Biology topics.
Related questions
In eukaryotes, primary mRNA transcript becomes mature mRNA afterIn prokaryotes, the small ribosomal subunit recognises the mRNA initiation site via theIn humans, the percentage of A in a DNA sample is 30 %. By Chargaff's rule, the percentageTranscription differs from replication in that itThe genetic code is described as degenerate becauseOkazaki fragments are formed on theDuring DNA replication, the enzyme that unwinds the double helix isSemiconservative DNA replication was experimentally demonstrated by