Griffith's 1928 transformation experiments used the bacterium:
- Escherichia coli
- Streptococcus pneumoniae
- Bacillus subtilis
- Mycobacterium tuberculosis
Show answer and solution
Correct answer: B. Streptococcus pneumoniae
Griffith worked with *Streptococcus pneumoniae* (S = smooth/virulent, R = rough/non-virulent strains).
Heat-killed S mixed with live R turned R into deadly S — the 'transforming principle' (later shown by Avery et al. to be DNA).