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Griffith's 1928 transformation experiments used the bacterium:

AEscherichia coli
BStreptococcus pneumoniae
CBacillus subtilis
DMycobacterium tuberculosis
Answer & Solution
Correct answer: B. Streptococcus pneumoniae
Griffith worked with *Streptococcus pneumoniae* (S = smooth/virulent, R = rough/non-virulent strains). Heat-killed S mixed with live R turned R into deadly S — the 'transforming principle' (later shown by Avery et al. to be DNA).
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