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In Griffith's transformation experiment, the 'transforming principle' was later identified by Avery, MacLeod and McCarty (1944) as:
AProtein
BRNA
CDNA
DLipopolysaccharide
Answer & Solution
Correct answer: C. DNA
Avery et al. selectively destroyed proteins (proteases), RNA (RNase) and DNA (DNase) in cell-free extracts of S strain. Only DNase eliminated the transformation — pinpointing DNA as the transforming principle.
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