Mutant haemoglobin in sickle-cell anaemia polymerises under low oxygen and changes RBC shape from
- Biconcave disc to sickle
- Sphere to flat disc
- Disc to cube shape
- Sickle to biconcave disc
Show answer and solution
Correct answer: A. Biconcave disc to sickle
Under low oxygen tension the polymerised haemoglobin distorts the biconcave red cell into an elongated sickle.