The posterior pituitary hormone that stimulates the strong uterine contractions of true labor, in a positive feedback loop with prostaglandins, is:
ARelaxin
BOxytocin
ChCG
DEstrogen
Answer & Solution
Correct answer: B. Oxytocin
1. As labor approaches, the posterior pituitary increases its secretion of a specific contraction-stimulating hormone.
2. The myometrium simultaneously increases its number of receptors for this hormone.
3. This hormone is oxytocin.
4. Oxytocin stimulates prostaglandin release from fetal membranes in a positive feedback loop, which further strengthens contractions, unlike relaxin, which instead loosens pelvic ligaments.
_Source: OpenStax Anatomy and Physiology (CC BY 4.0), Ch 28 "Development and Inheritance", p.1345 §Physiology of Labor_
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