A maternal deficiency of which B vitamin in early pregnancy is linked to neural tube defects such as spina bifida?
AVitamin B12
BThiamine
CFolate
DRiboflavin
Answer & Solution
Correct answer: C. Folate
1. The neural tube forms early in embryonic development from ectoderm, through a process called neurulation.
2. Proper closure of the neural tube depends on adequate maternal nutrition.
3. Folate specifically as critical for this healthy development.
4. A maternal folate deficiency in the first weeks of pregnancy is linked to neural tube defects, including spina bifida and anencephaly.
_Source: OpenStax Anatomy and Physiology (CC BY 4.0), Ch 28 "Development and Inheritance", p.1334 §Organogenesis_
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