Alcohol has a diuretic effect on the body primarily because it:
AIncreases aldosterone secretion
BDamages the kidney nephrons directly
CInhibits the release of ADH
DIncreases plasma osmolality
Answer & Solution
Correct answer: C. Inhibits the release of ADH
1. ADH normally promotes water reabsorption in the kidney collecting ducts.
2. A diuretic effect means increased urine output, which happens when less water is reabsorbed.
3. Alcohol works by inhibiting ADH release, so less water is reabsorbed and more is lost as urine.
4. Increased aldosterone would instead conserve sodium and water, the opposite effect, so that option is ruled out.
5. So inhibiting ADH release is the correct mechanism.
_Source: OpenStax Anatomy and Physiology (CC BY 4.0), Ch 26 "Fluid, Electrolyte, and Acid-Base Balance", p.1259 §Role of ADH_
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