When a naive B cell is stimulated by the TH2 pathway, what does it differentiate into?
AA cytotoxic T lymphocyte cell
BAn antibody-secreting plasma cell
CA natural killer immune cell
DA resting dendritic cell
Answer & Solution
Correct answer: B. An antibody-secreting plasma cell
1. When stimulated by the TH2 pathway, naive B cells differentiate into antibody-secreting plasma cells.
2. A plasma cell is an immune cell that secretes antibodies, arising from a B cell stimulated by antigens.
3. This activation and proliferation of B cells corresponding to one specific receptor variant is called clonal selection.
4. Cytotoxic T lymphocytes, natural killer cells, and dendritic cells are all separate immune cell types, not the differentiation outcome described here for a stimulated B cell.
_Source: OpenStax Biology (1st ed., CC BY 4.0), Ch 42 "The Immune System", section B Lymphocytes_
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