Which enzyme is described as the main controlled enzyme of glycolysis?
AHexokinase, the first enzyme
BPhosphofructokinase, the third
CPyruvate kinase, the last
DAldolase, the fourth enzyme
Answer & Solution
Correct answer: B. Phosphofructokinase, the third
1. Glycolysis is regulated at three key enzymatic steps rather than at every step.
2. Phosphofructokinase is the main enzyme controlled in glycolysis.
3. High levels of adenosine triphosphate, citrate, or a lower and more acidic pH decrease its activity.
4. Hexokinase begins the control chain but is not the main point of control.
_Source: OpenStax Biology (1st ed., CC BY 4.0), Ch 7 "Cellular Respiration", section 7.7 Regulation of Cellular Respiration_
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