Which molecules are most commonly used as allosteric effectors of respiratory enzymes?
AFatty acids and their salts
BNucleotides such as ATP and ADP
CSteroid hormones from the liver
DMetal ions such as sodium ions
Answer & Solution
Correct answer: B. Nucleotides such as ATP and ADP
1. Enzymes catalysing the first committed reaction of a pathway are controlled by molecules binding an allosteric site.
2. The molecules most commonly used in this capacity are nucleotides such as adenosine triphosphate and adenosine diphosphate.
3. These effectors may increase or decrease enzyme activity depending on prevailing conditions.
4. Using the energy nucleotides as signals lets the pathway read the cell's energy state directly.
_Source: OpenStax Biology (1st ed., CC BY 4.0), Ch 7 "Cellular Respiration", section 7.7 Regulation of Cellular Respiration_
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