alleryStart learning →What is the net gain to the cell from glycolysis after the initial investment is repaid?
AFour ATP and two NADH molecules
BTwo ATP and four NADH molecules
CTwo ATP and two NADH molecules
DOne ATP and one NADH molecule
Answer & Solution
Correct answer: C. Two ATP and two NADH molecules
1. Two adenosine triphosphate molecules are used in the first half to prepare the six-carbon ring for cleavage.
2. Four are formed in the second half by substrate-level phosphorylation.
3. Subtracting the investment leaves a net gain of two adenosine triphosphate molecules and two NADH molecules.
4. Four adenosine triphosphate is the gross figure, which ignores the two spent at the start.
_Source: OpenStax Biology (1st ed., CC BY 4.0), Ch 7 "Cellular Respiration", section 7.2 Glycolysis_
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