alleryStart learning →In type 2 diabetes, reduced oxidation efficiency of NADH affects which part of cellular respiration?
AGlycolysis in the cytoplasm only
BThe citric acid cycle stage only
COxidative phosphorylation only
DEvery stage of respiration alike
Answer & Solution
Correct answer: C. Oxidative phosphorylation only
1. Mitochondrial diseases are genetic disorders of metabolism that leave body cells producing less energy than normal.
2. In type 2 diabetes the oxidation efficiency of NADH is reduced.
3. That reduced efficiency impacts oxidative phosphorylation but not the other steps of respiration.
4. Glycolysis is untouched because it does not depend on oxidizing NADH at the electron transport chain.
5. The citric acid cycle is likewise named as unaffected, so an answer naming it alone is wrong.
6. An answer claiming every stage is hit equally overstates a defect that is stated to be selective.
_Source: OpenStax Biology (1st ed., CC BY 4.0), Ch 7 "Cellular Respiration", section 7.1 Energy in Living Systems_
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