alleryStart learning →Which antibodies circulate in the plasma of a person with type O blood?
AThe anti-A antibody only
BThe anti-B antibody only
CNeither of the two
DBoth anti-A and anti-B
Answer & Solution
Correct answer: D. Both anti-A and anti-B
1. Type O erythrocytes lack both the A and the B antigen.
2. Neither antigen is therefore self for this person.
3. Preformed antibodies exist against every ABO antigen the person does not carry.
4. Both anti-A and anti-B antibodies consequently circulate in type O plasma, and that plasma load is exactly why type O donation still carries a residual risk.
_Source: OpenStax Anatomy and Physiology (CC BY 4.0), Ch 18 "The Cardiovascular System: Blood", section 18.6 Blood Typing_
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