alleryStart learning →Hemophilia C differs from the other forms in which two ways?
AIt is X-linked and involves factor VIII
BIt is autosomal and involves factor VIII
CIt is X-linked and involves factor XI
DIt is autosomal and involves factor XI
Answer & Solution
Correct answer: D. It is autosomal and involves factor XI
1. Hemophilia C is triggered by an autosomal chromosome rather than a sex chromosome.
2. The factor it renders nonfunctional is factor XI.
3. It is also not a true recessive condition, since even a single copy of the mutant gene gives a bleeding tendency.
4. Factor VIII belongs to hemophilia A, so any option naming it describes a different disease.
_Source: OpenStax Anatomy and Physiology (CC BY 4.0), Ch 18 "The Cardiovascular System: Blood", section 18.5 Hemostasis_
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