alleryStart learning →How do the completion times of the two initial coagulation pathways compare?
AExtrinsic in seconds, intrinsic in minutes
BExtrinsic in minutes, intrinsic in seconds
CBoth complete in a matter of seconds
DBoth complete in a matter of minutes
Answer & Solution
Correct answer: A. Extrinsic in seconds, intrinsic in minutes
1. The extrinsic pathway is short, running from factor III through factor VII to factor X.
2. Its events are completed in a matter of seconds.
3. The intrinsic pathway is longer and more complex, running from factor XII through XI and IX, then with factor VIII to factor X.
4. Its events are completed in a few minutes.
5. So the shorter chain is the faster one, which is a useful way to recall the pairing rather than memorising it flat.
_Source: OpenStax Anatomy and Physiology (CC BY 4.0), Ch 18 "The Cardiovascular System: Blood", section 18.5 Hemostasis_
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