alleryStart learning →Calcium ion is designated factor IV. From where is it derived?
AFrom the liver and from the platelets
BFrom the diet and from bone breakdown
CFrom the kidneys and from the spleen
DFrom the marrow and from the plasma
Answer & Solution
Correct answer: B. From the diet and from bone breakdown
1. Most clotting factors are proteins secreted by the liver and the platelets.
2. Factor IV is different because it is an inorganic ion rather than a protein.
3. An ion is not synthesised, so it must be supplied, and it comes from the diet and from the breakdown of bone.
4. Calcium is required across the entire process rather than in one pathway only.
5. The liver and platelet option is the trap, because it is the correct answer for the protein factors and a candidate may generalise it.
6. Neither the spleen nor the marrow is named as a calcium source for coagulation.
_Source: OpenStax Anatomy and Physiology (CC BY 4.0), Ch 18 "The Cardiovascular System: Blood", section 18.5 Hemostasis_
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