Which plasma glycoprotein helps stabilize the growing platelet plug?
AVon Willebrand factor
BTissue thromboplastin
CPlasma antithrombin
DPlasma ceruloplasmin
Answer & Solution
Correct answer: A. Von Willebrand factor
1. Platelets meeting exposed collagen at a rupture become spiked and sticky and begin to clump.
2. A plasma glycoprotein called von Willebrand factor assists that process and stabilises the growing plug.
3. Tissue thromboplastin is factor III, which starts the extrinsic coagulation pathway rather than the plug.
4. Antithrombin opposes clotting, so it works against rather than for the plug.
5. Ceruloplasmin transports copper and has no role in hemostasis at all.
_Source: OpenStax Anatomy and Physiology (CC BY 4.0), Ch 18 "The Cardiovascular System: Blood", section 18.5 Hemostasis_
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