How does acute leukemia differ from chronic leukemia in the cells that accumulate?
AAcute has immature cells, chronic mature
BAcute has mature cells, chronic immature
CBoth accumulate only immature cells
DBoth accumulate only mature cells
Answer & Solution
Correct answer: A. Acute has immature cells, chronic mature
1. Leukemia is a cancer involving an abundance of leukocytes, from either the myeloid or the lymphoid line.
2. In chronic leukemia, mature leukocytes accumulate because they fail to die.
3. In acute leukemia, young immature leukocytes are overproduced.
4. So the acute form is defined by immaturity and the chronic form by failure of turnover.
5. In both conditions the cells do not function properly, so cell count alone never means competent defence.
6. The reversed option is the trap and can be caught by remembering that an acute course fits the more primitive cell.
_Source: OpenStax Anatomy and Physiology (CC BY 4.0), Ch 18 "The Cardiovascular System: Blood", section 18.4 Leukocytes and Platelets_
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