What are monocytes called after they leave the circulation?
AMegakaryocytes
BMast cells
CMacrophages
DMyeloblasts
Answer & Solution
Correct answer: C. Macrophages
1. Monocytes are agranular leukocytes of the myeloid line that circulate in the bloodstream.
2. Once they leave the circulation they are called macrophages.
3. As macrophages they phagocytize debris, pathogens and worn-out erythrocytes, and release defensins and chemotactic signals.
4. Mast cells develop from a different lineage entirely, so a monocyte never becomes one.
_Source: OpenStax Anatomy and Physiology (CC BY 4.0), Ch 18 "The Cardiovascular System: Blood", section 18.4 Leukocytes and Platelets_
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