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Which pair of substances do basophil granules release?

ALysozyme and hydrogen peroxide
BHistamine and heparin
CAntihistamine and defensins
DSerotonin and prostaglandins
Answer & Solution
Correct answer: B. Histamine and heparin
1. Basophils intensify the inflammatory response, a trait they share with mast cells. 2. Their granules release histamines, which contribute to inflammation. 3. The same granules release heparin, which opposes blood clotting. 4. So one basophil product drives inflammation and the other is an anticoagulant. 5. Lysozyme, oxidants and defensins are neutrophil weapons, not basophil ones. 6. Antihistamine is the eosinophil product that counteracts the basophil histamine, so that option is the exact inversion of the answer. 7. Serotonin and prostaglandins are released by platelets during plug formation, so they belong to hemostasis rather than to a granulocyte. _Source: OpenStax Anatomy and Physiology (CC BY 4.0), Ch 18 "The Cardiovascular System: Blood", section 18.4 Leukocytes and Platelets_
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