Where do B cells and T cells complete their maturation?
AB cells in bone marrow, T cells in thymus
BBoth in the thymus after leaving marrow
CB cells in thymus, T cells in bone marrow
DBoth in the spleen and the lymph nodes
Answer & Solution
Correct answer: A. B cells in bone marrow, T cells in thymus
1. Both cell lines start as lymphoid stem cells in the bone marrow.
2. Lymphoid stem cells migrate quickly out of the marrow towards lymphatic tissue including the lymph nodes, spleen and thymus.
3. B cells complete maturation in the bone marrow, and the letter B carries that meaning.
4. T cells complete maturation in the thymus, and the letter T carries that meaning.
5. The reversed option swaps the two sites and relies on a candidate not linking the letters to the organs.
6. The spleen and lymph nodes host later production and reproduction of lymphocytes, but they are not where either line first matures.
_Source: OpenStax Anatomy and Physiology (CC BY 4.0), Ch 18 "The Cardiovascular System: Blood", section 18.2 Production of the Formed Elements_
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