alleryStart learning →Why is glycolysis the only route by which erythrocytes make ATP?
AThey lack the enzyme carbonic anhydrase
BThey lack a nucleus to make the enzymes
CThey lack any glucose transporter protein
DThey lack mitochondria for oxidative steps
Answer & Solution
Correct answer: D. They lack mitochondria for oxidative steps
1. Most cells make the bulk of their ATP through oxidative stages held in mitochondria.
2. Erythrocytes do not contain mitochondria.
3. Glycolysis is therefore the sole method by which they produce ATP.
4. That is also why BPG, a byproduct of glycolysis, accumulates in these cells.
5. Erythrocytes are rich in carbonic anhydrase, so the first option states the opposite of the truth.
6. Glucose must still enter the cell for glycolysis to run at all, which rules out the third option.
_Source: OpenStax Anatomy and Physiology (CC BY 4.0), Ch 22 "The Respiratory System", section 22.5 Transport of Gases_
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