alleryStart learning →In what order does a charged tRNA pass through the three compartments of the ribosome?
AE site, then P site, then A site
BP site, then A site, then E site
CA site, then E site, then P site
DA site, then P site, then E site
Answer & Solution
Correct answer: D. A site, then P site, then E site
1. The A site, named for aminoacyl, binds incoming charged tRNAs.
2. The tRNA then shifts to the P site, named for peptidyl, where its amino acid joins the growing chain.
3. It moves on to the E site, named for exit, which releases it for recharging.
4. Each single-codon step of the ribosome moves every bound tRNA one place along this path.
_Source: OpenStax Biology (1st ed., CC BY 4.0), Ch 15 "Genes and Proteins", section 15.5 Ribosomes and Protein Synthesis_
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