alleryStart learning →What does the Shine-Dalgarno sequence do in an E. coli mRNA?
AIt marks the point where the mRNA is cut
BIt codes for the first amino acid added
CIt anchors the 30S subunit on the mRNA
DIt stops the ribosome at the gene end
Answer & Solution
Correct answer: C. It anchors the 30S subunit on the mRNA
1. The Shine-Dalgarno sequence AGGAGG lies upstream of the first AUG codon.
2. It interacts with the rRNA molecules that make up the ribosome.
3. That interaction anchors the 30S subunit at the correct place on the message.
4. It is not translated itself, since it sits upstream of the start codon rather than in frame with it.
_Source: OpenStax Biology (1st ed., CC BY 4.0), Ch 15 "Genes and Proteins", section 15.5 Ribosomes and Protein Synthesis_
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