alleryStart learning →Which processing step adds stability to pre-tRNAs and pre-rRNAs?
ACleavage of the long precursor
BSplicing of internal segments
CMethylation of some of the bases
DAddition of a long poly-A tail
Answer & Solution
Correct answer: C. Methylation of some of the bases
1. Structural RNAs are first made as long precursors that span several tRNAs or rRNAs.
2. Enzymes cleave those precursors into the individual molecules, which is a sizing step rather than a stabilising one.
3. Some bases are then methylated, and that methyl group is what is added for stability.
4. Pre-tRNA molecules undergo methylation as well, so the step applies to both classes.
_Source: OpenStax Biology (1st ed., CC BY 4.0), Ch 15 "Genes and Proteins", section 15.4 RNA Processing in Eukaryotes_
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