Where are introns removed from a pre-mRNA, and what becomes of them?
AIn the cytoplasm, and they are translated
BIn the nucleolus, and they are re-used
CIn the cytoplasm, and they are exported
DIn the nucleus, and they are degraded
Answer & Solution
Correct answer: D. In the nucleus, and they are degraded
1. Splicing happens while the pre-mRNA is still inside the nucleus.
2. The excised introns are degraded rather than kept or exported.
3. Only finished transcripts that have been capped, tailed and spliced leave for the cytoplasm.
4. Nothing about an intron is translated, so the option putting them on a ribosome is wrong.
_Source: OpenStax Biology (1st ed., CC BY 4.0), Ch 15 "Genes and Proteins", section 15.4 RNA Processing in Eukaryotes_
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