alleryStart learning →Which feature of a processed eukaryotic mRNA is recognized by the factors that begin translation?
AThe poly-A tail at the 3' end
BThe methylguanosine 5' cap
CThe introns spliced out of it
DThe AAUAAA sequence left behind
Answer & Solution
Correct answer: B. The methylguanosine 5' cap
1. Factors involved in protein synthesis recognize the 5' cap and use it to start translation by ribosomes.
2. In eukaryotes the initiation complex docks at that cap and then tracks along the message looking for AUG.
3. The poly-A tail protects the transcript and assists its export, so its role comes earlier and elsewhere.
4. Introns are removed and degraded in the nucleus, so they are not present to be recognized at all.
_Source: OpenStax Biology (1st ed., CC BY 4.0), Ch 15 "Genes and Proteins", section 15.4 RNA Processing in Eukaryotes_
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