alleryStart learning →Which modification is added to the 5' end of a eukaryotic pre-mRNA?
AA string of about 200 A residues
BAn AAUAAA consensus sequence
CA 7-methylguanosine cap
DA GU-rich signal sequence
Answer & Solution
Correct answer: C. A 7-methylguanosine cap
1. The 5' end of a growing pre-mRNA receives a 7-methylguanosine cap through a phosphate linkage.
2. The cap protects the transcript from degradation and assists translation.
3. The string of about 200 A residues is the poly-A tail, and it goes on the 3' end instead.
_Source: OpenStax Biology (1st ed., CC BY 4.0), Ch 15 "Genes and Proteins", section 15.4 RNA Processing in Eukaryotes_
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