alleryStart learning →How much DNA is wound around the eight histones of a single nucleosome?
A46 nucleotides
B80 nucleotides
C200 nucleotides
D146 nucleotides
Answer & Solution
Correct answer: D. 146 nucleotides
1. When a eukaryotic cell is not dividing, its genes sit in chromatin, a diffuse mass of DNA and protein.
2. The DNA is wound around charged histone proteins at repeated intervals to give nucleosomes.
3. Each nucleosome holds 146 nucleotides of DNA wound around eight histones.
4. Two hundred is the approximate length of a poly-A tail, so it belongs to mRNA processing rather than packaging.
5. Eighty is the approximate position of the CAAT box upstream of an initiation site, not a length of wound DNA.
6. Forty-six inverts the digits of the real figure and is the careless-reading trap.
_Source: OpenStax Biology (1st ed., CC BY 4.0), Ch 15 "Genes and Proteins", section 15.3 Eukaryotic Transcription_
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