alleryStart learning →What do the GC-rich and octamer boxes contribute to a eukaryotic promoter?
AThey are essential for any transcription at all
BThey mark the exact spot where synthesis starts
CThey terminate transcription at the end of a gene
DThey raise the efficiency of transcription initiation
Answer & Solution
Correct answer: D. They raise the efficiency of transcription initiation
1. The GC-rich box is GGCG and the octamer box is ATTTGCAT, and both may appear several times in one promoter.
2. They bind cellular factors that increase the efficiency of transcription initiation.
3. Both are nonessential, which rules out the option calling them required.
4. The initiation point is fixed by the +1 site and the nearby TATA box, so these boxes do not mark it.
_Source: OpenStax Biology (1st ed., CC BY 4.0), Ch 15 "Genes and Proteins", section 15.3 Eukaryotic Transcription_
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