Which class of transcripts does RNA polymerase II make?
AThe 5S ribosomal RNA molecules
BThe transfer RNA precursors
CThe protein-coding pre-mRNAs
DThe small nuclear RNA molecules
Answer & Solution
Correct answer: C. The protein-coding pre-mRNAs
1. RNA polymerase II sits in the nucleus proper rather than the nucleolus.
2. It synthesizes all protein-coding nuclear pre-mRNAs.
3. Because most genes encode proteins, this enzyme transcribes the overwhelming majority of eukaryotic genes.
_Source: OpenStax Biology (1st ed., CC BY 4.0), Ch 15 "Genes and Proteins", section 15.3 Eukaryotic Transcription_
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