alleryStart learning →Which RNAs does RNA polymerase I synthesize?
AAll of the tRNAs and the 5S rRNA
BAll of the rRNAs except the 5S rRNA
CAll of the protein-coding pre-mRNAs
DAll of the small nuclear RNA classes
Answer & Solution
Correct answer: B. All of the rRNAs except the 5S rRNA
1. RNA polymerase I works in the nucleolus, where ribosomal RNA is transcribed, processed and assembled into ribosomes.
2. It synthesizes all of the rRNAs except for the 5S rRNA molecule.
3. The 5S rRNA is left to RNA polymerase III, along with the tRNAs and small nuclear RNAs.
4. Protein-coding pre-mRNAs belong to RNA polymerase II, so that option names the wrong enzyme.
_Source: OpenStax Biology (1st ed., CC BY 4.0), Ch 15 "Genes and Proteins", section 15.3 Eukaryotic Transcription_
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